Publications

Selected publications

Lindh E, Lounela H, Ikonen N, Kantala T, Savolainen-Kopra C, Kauppinen A, Österlund P, Kareinen L, Katz A, Nokireki T, Jalava J, London L, Pitkäpaasi M, Vuolle J Punto-Luoma A-L, Kaarto R, Voutilainen L, Holopainen R, Kalin-Mänttäri L, Laaksonen T, Kiviranta H, Pennanen A, Helve O, Laamanen I, Melin M, Tammiranta N, Rimhanen-Finne R, Gadd T, Salminen M.
Highly pathogenic avian influenza A(H5N1) virus infection on multiple fur farms in the South and Central Ostrobothnia regions of Finland, July 2023. Euro Surveill. 2023, doi.org/10.2807/1560-7917.ES.2023.28.31.2300400

Jiang M, Väisänen E, Kolehmainen P, Huttunen M, Ylä-Herttuala S, Meri S, Österlund P, Julkunen
I. COVID-19 adenovirus vector vaccine induces higher interferon and pro-inflammatory responses
than mRNA vaccines in human PBMCs, macrophages and moDCs. Vaccine 2023, doi.org/10.1016/j.vaccine.2023.04.049

Väisänen E, Jiang M, Laine L, Waris M, Julkunen I, Österlund P. Infectious viruses from transfected SARS-CoV-2 genomic RNA. Front Bioeng Biotechnol 2023: doi.org/10.3389/fbioe.2023.1129111

Laine L, Skön M, Väisänen E, Julkunen I, Österlund P. SARS-CoV-2 variants Alpha, Beta, Delta and Omicron show a slower host cell interferon response compared to an early pandemic variant in a human lung epithelial cell infection model. Front Immunol 2022, doi: 10.3389/fimmu.2022.1016108

Avelin V, Sissonen S, Julkunen I, Österlund P. Inactivation efficacy of H5N1 avian influenza virus by commonly used sample preparation reagents for safe laboratory practices. J Virol Met 2022: doi: 10.1016/j.jviromet.2022.114527

Belik M, Jalkanen P, Lundberg R, Reinholm A, Laine L, Väisänen E, Skön M, Tähtinen P, Ivaska L, Pakkanen S, Häkkinen H, Ortamo E, Pasternack A, Ritvos M, Nevas RA, Miettinen S, Sironen T, Vapalahti O, Ritvos O, Österlund P, Kantele A, Lempainen J, Kakkola L, Kolehmainen P, Julkunen I. Comparative analysis of COVID-19 vaccine responses and third booster dose-induced neutralizing antibodies against Delta and Omicron variants. Nat Communi 2022: doi.org/10.1038/s41467-022-30162-5

Jiang M, Kolehmainen P, Kakkola L, Maljanen S, Melén K, Smura T, Julkunen I, Österlund P. SARS-CoV-2 isolates show impaired replication in human immune cells but differential ability to replicate and induce innate immunity in lung epithelial cells. Mic Spectrum 2021: doi.org/10.1128/Spectrum.00774-21

Cantuti-Castelvetri, L, Ojha R, Pedro LD, Djannatian M, Franx J, Kuivanen S, Kallio K, Kaya T, Anastasina M, Smura T, Levanov L, Szirovicza L, Tobi A, Kallio-Kokko H, Österlund P, Joensuu M, Meunier FA, Butcher S, Winkler MS, Mollenhauer B, Helenius A, Gokce O, Teesalu T, Hepojoki J, Vapalahti O, Stadelmann C, Balistreri G, Simons M. Neuropilin-1 facilitates SARS-CoV-2 cell entry and provides a possible pathway into the central nervous system. Science. 2020 DOI: 10.1126/science.abd2985

Haveri A, Smura T, Kuivanen S, Österlund P, Hepojoki J, Ikonen N, Pitkäpaasi M, Blomqvist S, Rönkkö E, Kantele A, Strandin T, Kallio-Kokko H, Mannonen L, Lappalainen M, Broas M, Jiang M, Siira L, Salminen M, Puumalainen T, Sane J, Melin M, Vapalahti O, Savolainen-Kopra C. Serological and molecular findings during SARS-CoV-2 infection: the first case study in Finland, January to February 2020. Euro Surveill, 2020: doi.org/10.2807/1560-7917.ES.2020.25.11.2000266.

Jiang M, Österlund P, Poranen M, Julkunen I. In vitro production of synthetic viral RNAs and their delivery into mammalian cells, and the application of viral RNAs in the study of innate interferon responses. Methods, 2019: doi: 10.1016/j.ymeth.2019.10.013

Österlund P, Jiang M, Westenius V, Kuivanen S, Järvi R, Kakkola L, Lundberg R, Melén K, Korva M, Avšič - Županc T, Vapalahti O, Julkunen I. Asian and African lineage Zika viruses show differential replication and innate immune responses in human dendritic cells and macrophages. Sci Rep, 2019: doi: 10.1038/s41598-019-52307-1.

Westenius V, Mäkelä SM, Julkunen I, Österlund P. Highly pathogenic H5N1 influenza A virus spreads efficiently in human primary monocyte-derived macrophages and dendritic cells. Front Immunol, 2018: doi: 10.3389/fimmu.2018.01664. 

Jiang M, Österlund P, Westenius V, Guo D, Poranen M, Bamford DH, Julkunen I. Efficient inhibition of avian and seasonal influenza A viruses by a virus-specific Dicer-substrate siRNA swarm in human monocyte-derived macrophages and dendritic cells. J Virol, 2018, doi: 10.1128/JVI.01916-18.