Publications by study design

Cross-sectional study

Prospective cohort study

Retrospective cohort study

Nested case-control study

Repeated measurement study

Meta-analysis

Health follow-up

Quality control

Cross-sectional study

Heliövaara M, Mäkelä M, Knekt P, Impivaara O, Aromaa A. Determinants of sciatica and low-back pain. Spine 1991; 16: 608-614.

Mäkelä M, Heliövaara M, Sievers K, Impivaara O, Knekt P, Aromaa A. Prevalence, determinants, and consequences of chronic neck pain in Finland. Am J Epidemiol 1991; 134: 1356-1367.

Sulkava R, Wikström J, Aromaa A et al. Prevalence of severe dementia in Finland. Neurology 1985; 35: 1025-1029.

Prospective cohort study

Aromaa A, Raitasalo R, Reunanen A et al. Depression and cardiovascular diseases. Acta Psychiatr Scand Suppl 1994; 377: 77-82.

Heliövaara M, Aho K, Aromaa A, Knekt P, Reunanen A. Smoking and risk of rheumatoid arthritis. J Rheumatol 1993; 20: 1830-1835.

Joukamaa M, Heliövaara M, Knekt P, Aromaa A, Raitasalo R, Lehtinen V. Mental disorders and cause-specific mortality. Br J Psychiatry 2001; 179: 498-502.

Joukamaa M, Heliövaara M, Knekt P, Aromaa A, Raitasalo R, Lehtinen V. Schizophrenia, neuroleptic medication and mortality. Br J Psychiatry 2006; 188: 122-127.

Knekt P, Aromaa A, Maatela J et al. Serum selenium and subsequent risk of cancer among Finnish men and women. J Natl Cancer Inst 1990; 82: 864-868.

Knekt P, Kumpulainen J, Järvinen R et al. Flavonoid intake and risk of chronic diseases. Am J Clin Nutr 2002; 76: 560-568.

Knekt P, Reunanen A, Järvinen R, Seppänen R, Heliövaara M, Aromaa A. Antioxidant vitamin intake and coronary mortality in a longitudinal population study. Am J Epidemiol 1994; 139: 1180-1189.

Knekt P, Reunanen A, Takkunen H, Aromaa A, Heliövaara M, Hakulinen T. Body iron stores and risk of cancer. Int J Cancer 1994; 56: 379-382.

Knekt P, Järvinen R, Seppänen R, Pukkala E, Aromaa A. Intake of dairy products and the risk of breast cancer. Br J Cancer 1996; 73: 687-691.

Knekt P, Kilkkinen A, Rissanen H, Marniemi J, Sääksjärvi K, Heliövaara M. Serum vitamin D and the risk of Parkinson disease. Arch Neurol 2010; 67: 808-811.

Knekt P, Adlercreutz H, Rissanen H, Aromaa A, Teppo L, Heliövaara M. Does antibacterial treatment for urinary tract infection contribute to the risk of breast cancer? Br J Cancer 2000; 82: 1107-1110.

Lohi S, Mustalahti K, Kaukinen K et al. Increasing prevalence of coeliac disease over time. Aliment Pharmacol Ther 2007; 26: 1217-1225.

Montonen J, Knekt P, Järvinen R, Aromaa A, Reunanen A. Whole-grain and fiber intake and the incidence of type 2 diabetes. Am J Clin Nutr 2003; 77: 622-629.

Reunanen A, Takkunen H, Aromaa A. Prevalence of intermittent claudication and its effect on mortality. Acta Med Scand 1982; 211: 249-256.

Rissanen A, Heliövaara M, Knekt P, Reunanen A, Aromaa A, Maatela J. Risk of disability and mortality due to overweight in a Finnish population. BMJ 1990; 301: 835-837.

Tikkanen JT, Junttila MJ, Anttonen O et al. Early repolarization electrocardiographic phenotypes associated with favorable long-term outcome. Circulation 2011; 12: 2666-2673.

Retrospective cohort study

Tikkanen JT, Anttonen O, Junttila MJ et al. Long-term outcome associated with early repolarization on electrocardiography. N Engl J Med 2009; 361: 2529-37.

Nested case-control study

Aromaa A, Kosunen TU, Knekt P et al. Circulating anti-Helicobacter pylori immunoglobulin A antibodies and low serum pepsinogen I level are associated with increased risk of gastric cancer. Am J Epidemiol 1996; 144: 142-149.

Aho K, Heliövaara M, Knekt P et al. Serum immunoglobulins and the risk of rheumatoid arthritis. Ann Rheum Dis 1997; 56: 351-356.

Heikkilä R, Aho K, Heliövaara M et al. Serum androgen-anabolic hormones and the risk of rheumatoid arthritis. Ann Rheum Dis 1998; 57: 281-285.

Heliövaara M, Knekt P, Aho K, Aaran RK, Alfthan G, Aromaa A. Serum antioxidants and risk of rheumatoid arthritis. Ann Rheum Dis 1994; 53: 51-53.

Aho K, Palosuo T, Knekt P, Alha P, Aromaa A, Heliövaara M. Serum C-reactive protein does not predict rheumatoid arthritis. J Rheumatol 2000; 27: 1136-1138.

Knekt P, Heliövaara M, Aho K, Alfthan G, Marniemi J, Aromaa A. Serum selenium, serum alpha-tocopherol, and the risk of rheumatoid arthritis. Epidemiology 2000; 11: 402-405.

Aho K, Palosuo T, Heliövaara M, Knekt P, Alha P, von Essen R. Antifilaggrin antibodies within "normal" range predict rheumatoid arthritis in a linear fashion. J Rheumatol 2000; 27: 2743-2746.

Heliövaara M, Knekt P, Aromaa A. Incidence and risk factors of herniated lumbar interverte­bral disc or sciatica leading to hospitalization. J Chronic Dis 1987; 40: 251‑258.

Knekt P, Aromaa A, Maatela J et al. Serum vitamin E and risk of cancer among Finnish men during a 10-year follow-up. Am J Epidem 1988; 127: 28‑41.

Knekt P, Reunanen A, Alfthan G et al. Hyperhomocystinemia: a risk factor or a consequence of coronary heart disease? Arch Intern Med 2001; 161: 1589-1594.

Koivula MK, Heliövaara M, Ramberg J et al. Autoantibodies binding to citrullinated telopeptide of type II collagen and to cyclic citrullinated peptides predict synergistically the development of seropositive rheumatoid arthritis. Ann Rheum Dis 2007; 66: 1450–1455.

Koivula M-K, Heliövaara M, Rissanen H et al. Antibodies binding to citrullinated telopeptides of type I and II collagens and to mutated citrullinated vimentin synergistically predict the development of seropositive rheumatoid arthritis. Ann Rheum Dis 2012; 71: 1666-1670.

Lehtinen M, Dillner J, Knekt P et al. Serologically diagnosed infection with human papillomavirus type 16 and risk for subsequent development of cervical carcinoma: nested case-control study. BMJ 1996; 312: 537-539.

Puisto V, Heliövaara M, Impivaara O et al. Severity of vertebral fracture and risk of hip fracture: a nested case-control study. Osteoporos Int 2011; 22: 63-68.

Pussinen PJ, Alfthan G, Rissanen H, Reunanen A, Asikainen S, Knekt P. Antibodies to periodontal pathogens and stroke risk. Stroke 2004; 35: 2020-2023.

Stenman UH, Hakama M, Knekt P, Aromaa A, Teppo L, Leinonen J. Serum concentrations of prostate specific antigen and its complex with alpha 1-antichymotrypsin before diagnosis of prostate cancer. Lancet 1994; 344: 1594-1598.

Tallroth K, Lohman M, Heliövaara M, Aromaa A, Knekt P, Standertskjöld-Nordenstam CG. Dextrocardia and coronal alignment of thoracic curve: a population study. Eur Spine J 2009; 18: 1941-1945.

Repeated measurement study

Knekt P, Marniemi J, Teppo L, Heliövaara M, Aromaa A. Is low selenium status a risk factor for lung cancer? Am J Epidemiol 1998; 148 :975-982.

Rissanen AM, Heliövaara M, Knekt P, Reunanen A, Aromaa A. Determinants of weight-gain and overweight in adult Finns. Eur J Clin Nutr 1991; 45: 419-430.

Meta-analysis

Bogers RP, Bemelmans WJ, Hoogenveen RT et al. Association of overweight with increased risk of coronary heart disease partly independent of blood pressure and cholesterol levels: a meta-analysis of 21 cohort studies including more than 300 000 persons. Arch Intern Med 2007; 167: 1720-1728.

Jakobsen MU, O'Reilly EJ, Heitmann BL et al. Major types of dietary fat and risk of coronary heart disease: a pooled analysis of 11 cohort studies. Am J Clin Nutr 2009; 89: 1425-1432.

Knekt P, Ritz J, Pereira MA et al. Antioxidant vitamins and coronary heart disease risk: a pooled analysis of 9 cohorts. Am J Clin Nutr 2004; 80: 1508-1520.

Global Burden of Metabolic Risk Factors for Chronic Diseases Collaboration (BMI Mediated Effects), Lu Y, Hajifathalian K et al. Metabolic mediators of the effect of body-mass index, overweight, and obesity on coronary heart disease and stroke: a pooled analysis of 97 prospective cohorts with 1.8 million participants. Lancet 2014; 383: 970-983.

Pereira MA, O'Reilly E, Augustsson K et al. Dietary fiber and risk of coronary heart disease: a pooled analysis of cohort studies. Arch Intern Med 2004; 164: 370-376.

Prospective Studies Collaboration, Whitlock G, Lewington S et al. Body-mass index and cause-specific mortality in 900 000 adults: collaborative analyses of 57 prospective studies. Lancet 2009; 373: 1083-1096.

Pukkala E, Andersen A, Berglund G et al. Nordic biological specimen banks as basis for studies of cancer causes and control--more than 2 million sample donors, 25 million person years and 100,000 prospective cancers. Acta Oncol 2007; 46: 286-307.

Qizilbash N, Lewington S, Duffy S et al. Cholesterol, diastolic blood pressure, and stroke: 13000 strokes in 450000 people in 45 prospective cohorts. Lancet 1995; 346: 1647-1653.

Helicobacter and Cancer Collaborative Group. Gastric cancer and Helicobacter pylori: a combined analysis of 12 case control studies nested within prospective cohorts. GUT 2001; 49: 347-353.

Health follow-up

Aromaa A, Koskinen S eds. Health and functional capacity in Finland. Baseline results of the Health 2000 Survey. Publications of the National Public Health Institute B12/2004.

Heliövaara M, Impivaara O, Nykyri E et al. Changes in morbidity. Julkaisussa: Kaila-Kangas L ed. Musculoskeletal disorders and diseases in Finland. Publications of the National Public Health Institute B 25/2007, Helsinki 2007: 60-69.

Kattainen A, Reunanen A, Koskinen S et al. Secular changes in disability among middle-aged and elderly Finns with and without coronary heart disease from 1978-1980 to 2000-2001. Ann Epidemiol 2004; 14: 479-485.

Lahti-Koski M, Seppänen-Nuijten E, Männistö S et al. Twenty-year changes in the prevalence of obesity among Finnish adults. Obes Rev 2010; 11: 171-176.

Rissanen A, Heliövaara M, Aromaa A. Overweight and anthropometric changes in adulthood: a prospective study of 17,000 Finns. Int J Obes 1988; 12: 391‑401.

Vasankari TM, Impivaara O, Heliövaara M et al. No increase in the prevalence of COPD in two decades. Eur Respir J 2010; 36: 766-773.

Quality control

Heliövaara M, Aromaa A, Klaukka T, Knekt P, Joukamaa M, Impivaara O. Reliability and validity of interview data on chronic diseases. The Mini-Finland Health Survey. J Clin Epidemiol 1993; 46: 181-191.

Järvinen R, Seppänen R, Knekt P. Short-term and long-term reproducibility of dietary history interview data. Int J Epidemiol 1993; 22: 520-527.

Seppänen R, Knekt P, Hasunen K  et al. Värdering av dietary history-metodens reliabilitet. Vår Föda Suppl. 1979; 4: 391-398.

Sääksjärvi K, Knekt P, Männistö S, Heliövaara M. Self-administered questionnaire is a reliable measure of coffee consumption. J Epidemiol 2010; 20: 363-369.