THL Diabetes Studies
THL has collected samples and data from diabetics and their family members in several studies between 1986 and 2010.
Type 1 diabetes is more common in Finland than in any other country in the world. Type 2 diabetes is even more common, but the incidence in Finland does not differ from other developed countries.
A combination of genetic and environmental risk factors are involved in the pathogenesis of both type 1 and type 2 diabetes although the diseases have different causes. The focus of the THL Diabetes studies have been on the genetic background and environmental triggers of diabetes in Finland.
Altogether THL Diabetes Study collection contains more than 13 500 sample donors, collected in the separate studies listed in the following table.
Sub-collection name | Number of sample donors in the original study | Age of the participants at sample collection | Specific features |
---|---|---|---|
DIME (1986-1989) |
2512 | 1- | Childhood Diabetes in Finland Participants were families with a type 1 diabetic child with an age of onset of diabetes under 15 years. |
IDDMGEN (1994-2006) |
8911 | 1- | Epidemiology and genetics of IDDM in Finland Focus on families with more than one diabetic member. |
T1D-GEN (2008-2010) |
962 | 18- | A genome-wide genetic analysis of childhood and adult onset type 1 diabetes (T1D) in Finland |
YA and YA-EPID |
2333 | 15-39 family members 1- |
The epidemiology and risk of diabetes among young Finns |
Samples and data available in THL Biobank
More information on the THL Diabetes Studies and description of the material available in THL Biobank can be found in the 'Read me first' file.
DNA sample is available for research from most participants and serum, plasma and PBMC samples from subsets. For more detailed information, please see the 'THL Biobank Sample availability table'.
Genome-wide SNP data is available for majority of the study participants, for more detailed information, please see the 'THL Biobank Omics availability table'.
The available phenotype data attributes are described in detail in the variable description files (on the right panel).
Additional information
If you are interested in sample collections focusing on diabetes, see also Botnia Study and FUSION Study in THL Biobank.
Botnia Study
FUSION Study
Access to samples and data
Availability queries and application process to access THL Biobank resources
Contact
admin.biobank (at) thl.fi
Collected during 1986—2010
Includes data on both affected and unaffected individuals
More than 13 500 sample donors (blood, serum, plasma, DNA, cells), aged 0–70 years old
Genome-wide SNP data available