THL Biobank is thrilled to announce its new polygenic risk score (PRS) service

Publication date 25 Mar 2022

THL Biobank's large dataset of 120,000 imputed genomes from several cohorts offers a possibility to build and use polygenic risk scores in biobank research studies. Polygenic risk scores have revolutionized a new approach to study the genetic architecture of common complex disorders. These scores are used to estimate the lifetime genetic risk of disease and they have shown to be useful in identifying individuals at highest risk, which could enable earlier disease risk screening. The power of categorizing individuals into different risk classes has raised an interest in using the polygenic risk score as a promising prognostic tool and its implementation into clinical approaches has already been suggested.

Genetic risk score for your research discoveries. A simplified illustration on how the personal PRS value for selected disease can be calculated using genotype data.

We are excited to release our first scores for Type 1 diabetes, Type 2 diabetes, and BMI, calculated for FINRISK Study participants. By combining the scores to standardized lifestyle, anthropometric and biomarker data, as well as the availability of clinical follow-up data from health registers creates unique research opportunities for true personalized medicine studies.
FINRISK Study in THL Biobank

Our polygenic risk score services will expand with new scores in the future, thus do not hesitate to be in contact with us and we will build a score for your specific research purposes!
Contact information for THL Biobank

THL Biopankki biobank - THL Biobank